Community-acquired pneumonia (CAP) caused by susceptible organisms eg, Legionella pneumophila & pelvic inflammatory disease (PID) caused by Chlamydia trachomatis, Neisseria gonorrhea, Mycoplasma hominis in patients who require initial IV therapy.
Adult CAP 500 mg IV single dose for 1-2 days, followed by 500 mg PO single daily dose to complete 7- to 10-day therapy. PID 500 mg IV single dose for 1-2 days, followed by 250 mg PO single daily dose to complete 7-day therapy.
Discontinue use if allergic reaction occurs. Not to be used as IV bolus or IM inj. Superinfection; Clostridium difficile-associated diarrhea. Congenital or documented QT prolongation, electrolyte disturbance (hypokalemia, hypomagnesemia), clinically relevant bradycardia, cardiac arrhythmia or insufficiency. Avoid co-administration w/ ergot derivatives. Concurrent use w/ class IA & III antiarrhythmics, antipsychotics, antidepressants & fluoroquinolones. Severe renal impairment (GFR <10 mL/min). Hepatic disease. Pregnancy. Not to be used during lactation. Childn. Elderly.
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